Structure of PDB 7xyb Chain C Binding Site BS01

Receptor Information
>7xyb Chain C (length=1190) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YSYTEKKRIRKDFSKLPDVMDVPYLLAIQLDSYREFLQAGATKEQFRDVG
LHAAFKSVFPIISYSGNAALEYVGYRLGEPAFDVKECVLRGVTFAVPLRV
KVRLIIFDRESSNKAIKDIKEQEVYMGEIPLMTENGTFIINGTERVIVSQ
LHRSPGVFFDHDRGKTHSSGKLLYSARIIPYRGSWLDFEFDPKDCVFVRI
DRRRKLPASVLLRALGYSTEEILNAFYATLYTNDIDCGPFISDTLKIDNT
SNQLEALVEIYRMMRPGEPPTKEAAETLFGNLFFSAERYDLSAVGRMKFN
RRIGRTEIEGPGVLSKEDIIDVLKTLVDIRNGKGIVDDIDHLGNRRVRCV
GEMAENQFRVGLVRVERAVKERLSMAESEGLMPQDLINAKPVAAAIKEFF
GSSQLSQFMDQNNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTHYG
RVCPIETPEGPNIGLINSLATYARTNKYGFLESPYRVVKDSLVTDEIVFL
SAIEEADHVIAQASATLNEKGQLVDELVAVRHLNEFTVKAPEDVTLMDVS
PKQVVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLRADKPLVGTGMER
NVARDSGVCVVARRGGVIDSVDASRVVVRVADDEVETGEAGVDIYNLTKY
TRSNQNTCINQRPLVSKGDVVARGDILADGPSTDMGELALGQNMRVAFMP
WNGFNFEDSICLSERVVQEDRFTTIHIQELTCVARDTKLGPEEITADIPN
VGEAALNKLDEAGIVYVGAEVQAGDILVGKVTPVKDTSLRVPTGTKGTVI
DVQVFTRDGVERDSRALSIEKMQLDQIRKDLNEEFRIVEGATFERLRAAL
VGAADDALNEQLEKAQAYISDRRQLLDDKFEDKKRKLQQGDDLAPGVLKI
VKVYLAIKRRIQPGDKMAGRHGNKGVVSVIMPVEDMPHDANGTPVDIVLN
PLGVPSRMNVGQILETHLGLAAKGLGEKINRMLEEQRKVAELRKFLHEIY
NEIGGREENLDELGDNEILALAKNLRGGVPMATPVFDGAKEREIKAMLKL
ADLPESGQMRLFDGRTGNQFERPTTVGYMYMLKLNHLVDDKMHARSTGSY
SLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGR
TKMYKNIVDGDHRMEAGMPESFNVLIKEIRSLGIDIELET
Ligand information
Receptor-Ligand Complex Structure
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PDB7xyb Structural basis of AlpA-dependent transcription antitermination.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		Q515 Q518 R545 P569 N573 R692 Q693 K1090 H1252
Binding residue
(residue number reindexed from 1)		Q404 Q407 R434 P458 N462 R581 Q582 K924 H1086
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7xyb, PDBe:7xyb, PDBj:7xyb
PDBsum7xyb
PubMed35871295
UniProtQ51561|RPOB_PSEAE DNA-directed RNA polymerase subunit beta (Gene Name=rpoB)

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