Structure of PDB 7wm4 Chain C Binding Site BS01

Receptor Information
>7wm4 Chain C (length=661) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CTVRYNVADCSHLKLTHIPDDLPSNITVLNLTHNQLRRLPPTNFTRYSQL
AILDAGFNSISKLEPELCQILPLLKVLNLQHNELSQISDQTFVFCTNLTE
LDLMSNSIHKIKSNPFKNQKNLIKLDLSHNGLSSTKLGTGVQLENLQELL
LAKNKILALRSEELEFLGNSSLRKLDLSSNPLKEFSPGCFQTIGKLFALL
LNNAQLNPHLTEKLCWELSNTSIQNLSLANNQLLATSESTFSGLKWTNLT
QLDLSYNNLHDVGNGSFSYLPSLRYLSLEYNNIQRLSPRSFYGLSNLRYL
SLKRAFTKSHPNIDDFSFQWLKYLEYLNMDDNNIPSTKSNTFTGLVSLKY
LSLSKTFTSLQTLTNETFVSLAHSPLLTLNLTKNHISKIANGTFSWLGQL
RILDLGLNEIEQKLSGQEWRGLRNIFEIYLSYNKYLQLSTSSFALVPSLQ
RLMLRRVALKNVDISPSPFRPLRNLTILDLSNNNIANINEDLLEGLENLE
ILDFQHNNLARLWNPGGPVNFLKGLSHLHILNLESNGLDEIPVGVFKNLF
ELKSINLGLNNLNKLEPFIFDDQTSLRSLNLQKNLITSVEKDVFGPPFQN
LNSLDMRFNPFDCTCESISWFVNWINQTHTNISELSTHYLCNTPHHYYGF
PLKLFDTSSCK
Ligand information
>7wm4 Chain A (length=81) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7wm4 TLR3 forms a laterally aligned multimeric complex along double-stranded RNA for efficient signal transduction.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		K42 H61 F85 H109 A520 R545 K620
Binding residue
(residue number reindexed from 1)		K14 H33 F57 H81 A486 R511 K583
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7wm4, PDBe:7wm4, PDBj:7wm4
PDBsum7wm4
PubMed36631495
UniProtQ99MB1|TLR3_MOUSE Toll-like receptor 3 (Gene Name=Tlr3)

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