Structure of PDB 7wfy Chain C Binding Site BS01
Receptor Information
>7wfy Chain C (length=105) Species:
9606
(Homo sapiens) [
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EIDYTAYPWFAGNMERQQTDNLLKSHASGTYLIRERPAEAERFAISIKFN
DEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLK
YPYKS
Ligand information
>7wfy Chain A (length=7) Species:
9606
(Homo sapiens) [
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NGYENPT
Receptor-Ligand Complex Structure
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PDB
7wfy
Vav2 is a novel APP-interacting protein that regulates APP protein level.
Resolution
2.449 Å
Binding residue
(original residue number in PDB)
R680 R698 R700 K718 H719 K721 T732 S755 F756 Q758
Binding residue
(residue number reindexed from 1)
R16 R34 R36 K54 H55 K57 T68 S91 F92 Q94
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7wfy
,
PDBe:7wfy
,
PDBj:7wfy
PDBsum
7wfy
PubMed
35882892
UniProt
P52735
|VAV2_HUMAN Guanine nucleotide exchange factor VAV2 (Gene Name=VAV2)
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