Structure of PDB 7w0t Chain C Binding Site BS01
Receptor Information
>7w0t Chain C (length=170) Species:
9606
(Homo sapiens) [
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VELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCG
FSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLNGGQ
YWAVTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQ
ERVFPLFSVCSTGTYLRIWP
Ligand information
>7w0t Chain E (length=5) Species:
12066
(Coxsackievirus) [
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EALFQ
Receptor-Ligand Complex Structure
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PDB
7w0t
A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures.
Resolution
1.57 Å
Binding residue
(original residue number in PDB)
T382 N383 T384 R385 A410 L423 F426 Q436 S499 C501 S502
Binding residue
(residue number reindexed from 1)
T41 N42 T43 R44 A69 L82 F85 Q95 S158 C160 S161
Enzymatic activity
Enzyme Commision number
2.3.2.27
: RING-type E3 ubiquitin transferase.
External links
PDB
RCSB:7w0t
,
PDBe:7w0t
,
PDBj:7w0t
PDBsum
7w0t
PubMed
35982226
UniProt
Q9C029
|TRIM7_HUMAN E3 ubiquitin-protein ligase TRIM7 (Gene Name=TRIM7)
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