Structure of PDB 7voc Chain C Binding Site BS01

Receptor Information
>7voc Chain C (length=327) Species: 68214 (Streptomyces griseochromogenes) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRERYLFIRLLEACNADCFMCDFALSRDTFRFSLEDFDELLPRAVEAGVG
YIRFTGGEPLMHTDVAELVRRGTDAGMKMSIITNGMMLPRQIERLADAGL
AQIIVSLDGGSAATHDVYRRSPGMFDNGLRGLRAAARLGVLPRVNSVVGP
HNYTEMPQLQRVLTEAGVRQWELSALKLERAISYPDPDHVRALCDPVYDA
DPEHMLVPLGKRFYGDTPEEQELYFSDSVTPRASAPLCHVVDDVIYLDGK
YGRAYACSCLPHREGDDEPGGAPLREDGVIRLDTPAFRTHADFFRTEGPR
VCNGCSTTAAGYSDDIARLGGVRPWQY
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain7voc Chain C Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7voc Radical S -Adenosyl Methionine Enzyme BlsE Catalyzes a Radical-Mediated 1,2-Diol Dehydration during the Biosynthesis of Blasticidin S.
Resolution2.62005 Å
Binding residue
(original residue number in PDB)		C31 C35 C38 A41 G74 N101 R136
Binding residue
(residue number reindexed from 1)		C14 C18 C21 A24 G57 N84 R119
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding

View graph for
Molecular Function
External links
PDB RCSB:7voc, PDBe:7voc, PDBj:7voc
PDBsum7voc
PubMed35238201
UniProtA0A1B1AYF2

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