Structure of PDB 7vf3 Chain C Binding Site BS01

Receptor Information
>7vf3 Chain C (length=494) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPV
LDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCEQRR
LGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYT
SRGVGGGIPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFA
RGASAYFLFLRRDLQAQSRAFRAYVSRVCLRDQHYYSYVELPLACEGGRY
GLIQAAAVATVAHGEVLFAAFSSAAPPTASGASALCAFPLDEVDRLANRT
RDACYTREGRAEDGTEVAYIEYDVNSDCAQLPVDTLDAYPCGSDHTPSPM
ASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPG
SDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHL
DCASCLAHRDPYCGWCVLLGRCSRRSECSPEQWLWSFQPELGCL
Ligand information
Receptor-Ligand Complex Structure
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PDB7vf3 De novo Fc-based receptor dimerizers differentially modulate PlexinB1 function.
Resolution2.29 Å
Binding residue
(original residue number in PDB)		H217 F244 Q277 A300 A301 P302 P303 T304 A315 Q404 A452 S454 R455 Q471
Binding residue
(residue number reindexed from 1)		H194 F221 Q254 A274 A275 P276 P277 T278 A279 Q368 A416 S418 R419 Q435
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0017154 semaphorin receptor activity
Biological Process
GO:0071526 semaphorin-plexin signaling pathway

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Molecular Function
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Biological Process
External links
PDB RCSB:7vf3, PDBe:7vf3, PDBj:7vf3
PDBsum7vf3
PubMed35981535
UniProtO43157|PLXB1_HUMAN Plexin-B1 (Gene Name=PLXNB1)

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