Structure of PDB 7usy Chain C Binding Site BS01

Receptor Information
>7usy Chain C (length=184) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GVFTREQLDEYQDCTFFTRKDIIRLYKRFYALNPHKVPTNMQGNRPAITT
LTFEEVEKMPELKENPFKRRICEVFSEDGRGNLSFDDFLDMFSVFSEMAP
LQLKLKYAFRIYDYDGDELLGHDDLSKMIRSLTRDELSDVEVEFIIERII
EEADLDGDSSINFAEFEHVVSRSPDFIRTFHIRI
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7usy Chain C Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7usy Structures of the TMC-1 complex illuminate mechanosensory transduction.
Resolution3.54 Å
Binding residue
(original residue number in PDB)
D132 D134 L136 D141
Binding residue
(residue number reindexed from 1)
D115 D117 L119 D124
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0005509 calcium ion binding
GO:0046872 metal ion binding
Biological Process
GO:0055074 calcium ion homeostasis

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:7usy, PDBe:7usy, PDBj:7usy
PDBsum7usy
PubMed36224384
UniProtQ93640

[Back to BioLiP]