Structure of PDB 7usx Chain C Binding Site BS01

Receptor Information
>7usx Chain C (length=184) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GVFTREQLDEYQDCTFFTRKDIIRLYKRFYALNPHKVPTNMQGNRPAITT
LTFEEVEKMPELKENPFKRRICEVFSEDGRGNLSFDDFLDMFSVFSEMAP
LQLKLKYAFRIYDYDGDELLGHDDLSKMIRSLTRDELSDVEVEFIIERII
EEADLDGDSSINFAEFEHVVSRSPDFIRTFHIRI
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7usx Chain C Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7usx Structures of the TMC-1 complex illuminate mechanosensory transduction.
Resolution3.09 Å
Binding residue
(original residue number in PDB)		D132 D134 L136 L137 G138 D141
Binding residue
(residue number reindexed from 1)		D115 D117 L119 L120 G121 D124
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0005509 calcium ion binding
GO:0046872 metal ion binding
Biological Process
GO:0055074 calcium ion homeostasis

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Molecular Function
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Biological Process
External links
PDB RCSB:7usx, PDBe:7usx, PDBj:7usx
PDBsum7usx
PubMed36224384
UniProtQ93640

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