Structure of PDB 7tts Chain C Binding Site BS01

Receptor Information
>7tts Chain C (length=456) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SNKDAALLEAARANNMQEVSRLLSEGADVNAKHRLGWTALMVAAINRNNS
VVQVLLAAGADPNLGSFKGCTALHYAVLADDYRTVKELLDGGANPLQRNE
MGHTPLDYAREGEVMKLLRTSEAKYQEKQRKREAEERRRFPLEQRLKEHI
IGQESAIATVGAAIRRKENGWYDEEHPLVFLFLGSSGIGKTELAKQTAKY
MHKDAKKGFIRLDMSEFQERHEVAKFIGSPPGYVGHEEGGQLTKKLKQCP
NAVVLFDEVDKAHPDVLTIMLQLFDEGRLTDGKGKTIDCKDAIFIMTSNV
ASDEIAQHALQLRQEALEISKNFKENVIRPILKAHFRRDEFLGRINEIVY
FLPFCHSELIQLVNKELNFWAKRAKQRHNITLLWDREVADVLVDGYNVHY
GARSIKHEVERRVVNQLAAAYEQDLLPGGCTLRITVEDSDKQLLKSPELP
SPQAEK
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7tts Chain C Residue 801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7tts Unique structural features govern the activity of a human mitochondrial AAA+ disaggregase, Skd3.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		T388 D454
Binding residue
(residue number reindexed from 1)		T191 D257
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.1.-
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:7tts, PDBe:7tts, PDBj:7tts
PDBsum7tts
PubMed36170828
UniProtQ9H078|CLPB_HUMAN Mitochondrial disaggregase (Gene Name=CLPB)

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