Structure of PDB 7tlt Chain C Binding Site BS01

Receptor Information
>7tlt Chain C (length=275) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFTTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDLQTRNVKAQSQTDRANLGTLRGYYNQSEAGSHTIQMMYG
CDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITQRKWEAA
RVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWASVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>7tlt Chain F (length=9) Species: 2697049 (Severe acute respiratory syndrome coronavirus 2) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
YFPLQSYGF
Receptor-Ligand Complex Structure
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PDB7tlt SARS-CoV-2 Spike-derived peptide S489-497 (YFPLQSYGF) presented by HLA-A*29:02
Resolution2.3 Å
Binding residue
(original residue number in PDB)		Y7 Q63 N66 Q70 T73 N77 L81 Y84 M97 Y99 R114 Y123 T143 K146 W147 V152 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)		Y7 Q63 N66 Q70 T73 N77 L81 Y84 M97 Y99 R114 Y123 T143 K146 W147 V152 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation

View graph for
Biological Process
External links
PDB RCSB:7tlt, PDBe:7tlt, PDBj:7tlt
PDBsum7tlt
PubMed36302758
UniProtB0UXQ0

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