Structure of PDB 7tjk Chain C Binding Site BS01

Receptor Information
>7tjk Chain C (length=544) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ADAQRSHYTVYPSLPHIPFVKLLSGKESEVNVEKRWELYHQLHSHFHDQV
DHIIDNIEADLKAEISDLLYSRCFNTIFLLGSDSTTKIELKDESSRYNVL
IELTPKESPNVRMMLRRSMYKLYSAADAEENDVSYDLSLVENFKRLFGKD
LAMVFNFKDVDSINFNTLDNFIILLKSAFKYDHVKISLIFNINTNLSNIE
KNLRQSTIRLLKRNYHKLDVSSNKGFKYGNQIFQSFLDTVDGKLNLSDRF
VEFILSKMANNTNHNLQLLTKMLDYSLMSYFFQNAFSVFIDPVNVDFLND
DYLKILSRCPTFMFFVEGLIKQHLEEFFVEFLVRENPINGHAKFVARFLE
EELNITNFNLIELYHNLLIGKLDSYLDRWSACKEYKDRLHFEPIDTIFQE
LFTLDNRSGLLTQSIFPSYKSNIEDNLLSWEQVLPSLSGDLDKIMAPVLG
QLFKLYREANMTINIYDFYIAFRETLPKEEILNFIRKDPSNTKLLELAET
PDAFDKVALILFMQAIFAFENMGLIKFQSTKSYDLVEKCVWRGI
Ligand information
>7tjk Chain G (length=41) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tacagattttatgtttagatcttttatgcttgcttttcaaa
Receptor-Ligand Complex Structure
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PDB7tjk A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		K134 R140 M141 R144 R145
Binding residue
(residue number reindexed from 1)		K106 R112 M113 R116 R117
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003688 DNA replication origin binding
GO:0005515 protein binding
Biological Process
GO:0006260 DNA replication
GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication
GO:0006270 DNA replication initiation
GO:0030466 silent mating-type cassette heterochromatin formation
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005656 nuclear pre-replicative complex
GO:0005664 nuclear origin of replication recognition complex
GO:0031261 DNA replication preinitiation complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7tjk, PDBe:7tjk, PDBj:7tjk
PDBsum7tjk
PubMed35217664
UniProtP54790|ORC3_YEAST Origin recognition complex subunit 3 (Gene Name=ORC3)

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