Structure of PDB 7t8q Chain C Binding Site BS01

Receptor Information
>7t8q Chain C (length=500) Species: 367110 (Neurospora crassa OR74A) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PEELPPAPRYFQGENTAGFMRPVRFEGDITNLEVVGEIPKSIEGTFYRVM
PEPHLPSFIPNDPWFNGDGNISGFYFKDGHVDLKQRYVRTEKFVREAEAR
RSLLGKYRNRYTDLVEFKIRSTANGNIVYWRGQLLALKEDSPPYAMDPET
LETFGVYDFDGQLPSLTFTAHPKFDPVTREMVCFGYEAKGDGTRDICYYS
FGPDGKIAETVWLVSPVCGMIHDFAVTENFVIFPIIPLVCDVERMKQGGD
HWQWDYSIPMYIGVLPRRGAQGSDVKWFEAPHGFAGHVANAFEDDKGHIQ
LQMAYAKDNVFFWWPDANGKGPRPGEVEAHFANFVLDYQSDKLPLAEPTY
LVDDDMEFPRIDDRVATRKHKHTFFCIFDRKPGVTDFEFVMPRAGGGAPM
SNGLAHLNHETGDIQRYLPGPRKLTGECIFIPRNSEAAEGDGYVMVLLAN
YEDMCSELAVLDTKDLTNEVALIKLPVRLRPGLHGNWVDKSDVDGHPAPL
Ligand information
Ligand IDFE2
InChIInChI=1S/Fe/q+2
InChIKeyCWYNVVGOOAEACU-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Fe+2]
CACTVS 3.341[Fe++]
FormulaFe
NameFE (II) ION
ChEMBL
DrugBankDB14510
ZINC
PDB chain7t8q Chain C Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7t8q CRYSTAL STRUCTURE OF T151G CAO1
Resolution2.15 Å
Binding residue
(original residue number in PDB)		H197 H248 H313 H510
Binding residue
(residue number reindexed from 1)		H171 H222 H287 H484
Annotation score1
Enzymatic activity
Enzyme Commision number 1.13.11.-
Gene Ontology
Molecular Function
GO:0010436 carotenoid dioxygenase activity
GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
Biological Process
GO:0016121 carotene catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7t8q, PDBe:7t8q, PDBj:7t8q
PDBsum7t8q
PubMed
UniProtQ7S860|CAO1_NEUCR Carotenoid cleavage oxygenase 1 (Gene Name=cao-1)

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