Structure of PDB 7rd1 Chain C Binding Site BS01

Receptor Information
>7rd1 Chain C (length=942) Species: 1123958 (Chimpanzee adenovirus Y25) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MATPSMLPQWAYMHIAGQDASEYLSPGLVQFARATDTYFSLGNKFRNPTV
APTHDVTTDRSQRLTLRFVPVDREDNTYSYKVRYTLAVGDNRVLDMASTY
FDIRGVLDRGPSFKPYSGTAYNSLAPKGAPNSSQWEQKKAGNGDTMETHT
FGVAPMGGENITIDGLQIGTDATADQDKPIYADKTFQPEPQVGEENWQET
ESFYGGRALKKDTSMKPCYGSYARPTNVKGGQAKLKVGADGVPTKEFDID
LAFFDTPGGTVNGQDEYKADIVMYTENTYLETPDTHVVYKPGKDDASSEI
NLVQQSMPNRPNYIGFRDNFIGLMYYNSTGNMGVLAGQASQLNAVVDLQD
RNTELSYQLLLDSLGDRTRYFSMWNQAVDSYDPDVRIIENHGVEDELPNY
CFPLDGSGTNAAYQGVKVKNGNDGDVESEWENDDTVAARNQLCKGNIFAM
EINLQANLWRSFLYSNVALYLPDSYKYTPANITLPTNTNTYDYMNGRVVP
PSLVDAYINIGARWSLDPMDNVNPFNHHRNAGLRYRSMLLGNGRYVPFHI
QVPQKFFAIKSLLLLPGSYTYEWNFRKDVNMILQSSLGNDLRTDGASISF
TSINLYATFFPMAHNTASTLEAMLRNDTNDQSFNDYLSAANMLYPIPANA
TNVPISIPSRNWAAFRGWSFTRLKTKETPSLGSGFDPYFVYSGSIPYLDG
TFYLNHTFKKVSITFDSSVSWPGNDRLLTPNEFEIKRTVDGEGYNVAQCN
MTKDWFLVQMLAHYNIGYQGFYVPEGYKDRMYSFFRNFQPMSRQVVDEVN
YKDYQAVTLAYQHNNSGFVGYLAPTMRQGQPYPANYPYPLIGKSAVTSVT
QKKFLCDRVMWRIPFSSNFMSMGALTDLGQNMLYANSAHALDMNFEVDPM
DESTLLYVVFEVFDVVRVHQPHRGVIEAVYLRTPFSAGNATT
Ligand information
>7rd1 Chain U (length=11) Species: 1123958 (Chimpanzee adenovirus Y25) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
DINFSSLAPRH
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7rd1 ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome.
Resolution3.07 Å
Binding residue
(original residue number in PDB)		Y636 S638 H763 R862 A874
Binding residue
(residue number reindexed from 1)		Y636 S638 H763 R862 A874
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Biological Process
GO:0046718 symbiont entry into host cell
GO:0075521 microtubule-dependent intracellular transport of viral material towards nucleus
Cellular Component
GO:0019028 viral capsid
GO:0039623 T=25 icosahedral viral capsid
GO:0042025 host cell nucleus
GO:0043657 host cell

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7rd1, PDBe:7rd1, PDBj:7rd1
PDBsum7rd1
PubMed34851659
UniProtG9G854

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