Structure of PDB 7q43 Chain C Binding Site BS01
Receptor Information
>7q43 Chain C (length=369) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
RTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAV
TVEGKVYACGEATNGRLGLGISSGTVPIPRQITALSSYVVKKVAVHSGGR
HATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACG
SSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVA
CGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGV
CQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGK
KIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLE
GQKITRVACGSSHSVAWTT
Ligand information
>7q43 Chain D (length=6) Species:
9606
(Homo sapiens) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
DADKDE
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
7q43
Crystal structure of RCC1-Like domain 2 of ubiquitin ligase HERC2 in complex with DXDKDED motif of dedicator of cytokinesis protein 10
Resolution
2.40002 Å
Binding residue
(original residue number in PDB)
K3002 R3161 A3214 K3231 Y3234 R3236 L3267 D3285 H3286 S3318
Binding residue
(residue number reindexed from 1)
K45 R204 A257 K274 Y277 R279 L310 D328 H329 S361
Enzymatic activity
Enzyme Commision number
2.3.2.26
: HECT-type E3 ubiquitin transferase.
External links
PDB
RCSB:7q43
,
PDBe:7q43
,
PDBj:7q43
PDBsum
7q43
PubMed
UniProt
O95714
|HERC2_HUMAN E3 ubiquitin-protein ligase HERC2 (Gene Name=HERC2)
[
Back to BioLiP
]
