Structure of PDB 7q3o Chain C Binding Site BS01
Receptor Information
>7q3o Chain C (length=63) Species:
9606
(Homo sapiens) [
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TRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKI
WFQNRRAKERKVN
Ligand information
>7q3o Chain B (length=18) [
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ttgtgttttatgacgtcc
Receptor-Ligand Complex Structure
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PDB
7q3o
Structure of CDX1 bound to hydroxymethylated DNA
Resolution
2.78 Å
Binding residue
(original residue number in PDB)
T183 R184 T185 R190 V191 Y193 R198 R228 Q229 I232 N236 K240
Binding residue
(residue number reindexed from 1)
T1 R2 T3 R8 V9 Y11 R16 R46 Q47 I50 N54 K58
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0000981
DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677
DNA binding
Biological Process
GO:0006355
regulation of DNA-templated transcription
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Molecular Function
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Biological Process
External links
PDB
RCSB:7q3o
,
PDBe:7q3o
,
PDBj:7q3o
PDBsum
7q3o
PubMed
UniProt
P47902
|CDX1_HUMAN Homeobox protein CDX-1 (Gene Name=CDX1)
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