Structure of PDB 7po6 Chain C Binding Site BS01

Receptor Information
>7po6 Chain C (length=166) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRS
ARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVF
KIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFP
PDESIDLYQVIHKMRH
Ligand information
Receptor-Ligand Complex Structure
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PDB7po6 Structural effects of m6A modification of the Xist A-repeat AUCG tetraloop and its recognition by YTHDC1.
Resolution1.77 Å
Binding residue
(original residue number in PDB)
K361 S362 N363 N367 W377 S378 L380 R404 E405 W428 K472 I473 G474 R475 D476
Binding residue
(residue number reindexed from 1)
K18 S19 N20 N24 W34 S35 L37 R61 E62 W85 K129 I130 G131 R132 D133
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

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Molecular Function
External links
PDB RCSB:7po6, PDBe:7po6, PDBj:7po6
PDBsum7po6
PubMed35166835
UniProtQ96MU7|YTDC1_HUMAN YTH domain-containing protein 1 (Gene Name=YTHDC1)

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