Structure of PDB 7pmq Chain C Binding Site BS01

Receptor Information
>7pmq Chain C (length=458) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GMTAFSTLNVLPPAQLTNLNELGYLTMTPVQAAALPAILAGKDVRVQAKT
GSGKTAAFGLGLLQQIDASLFQTQALVLCPTRELADQVAGELRRLARFLP
NTKILTLCGGQPFGMQRDSLQHAPHIIVATPGRLLDHLQKGTVSLDALNT
LVMDEADRMLDMGFSDAIDDVIRFAPASRQTLLFSATWPEAIAAISGRVQ
RDPLAIEIDSTDALPPIEQQFYETSSKGKIPLLQRLLSLHQPSSCVVFCN
TKKDCQAVCDALNEVGQSALSLHGDLEQRDRDQTLVRFANGSARVLVATD
VAARGLDIKSLELVVNFELAWDPEVHVHRIGRTARAGNSGLAISFCAPEE
AQRANIISDMLQIKLNWQTPPANSSIATLEAEMATLCIDGGKKAKMRPGD
VLGALTGDIGLDGADIGKIAVHPAHVYVAVRQAVAHKAWKQLQGGKIKGK
TCRVRLLK
Ligand information
>7pmq Chain E (length=42) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gggaaggguuucgacccuucccaauauggcuguucgccauuu
<<<<<<<<<....>>>>>>>>><<.<<<<<.....>>>>>>>
Receptor-Ligand Complex Structure
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PDB7pmq Structural basis for RNA-duplex unwinding by the DEAD-box helicase DbpA.
Resolution3.22 Å
Binding residue
(original residue number in PDB)		P79 T80 R81 C107 G108 P111 G113 T129 G131 R132 R157 G162 F163 N249 T250 K251 H272 G273 R280 T298 W320
Binding residue
(residue number reindexed from 1)		P80 T81 R82 C108 G109 P112 G114 T130 G132 R133 R158 G163 F164 N250 T251 K252 H273 G274 R281 T299 W321
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0019843 rRNA binding
GO:0033677 DNA/RNA helicase activity
GO:0034458 3'-5' RNA helicase activity
GO:0043531 ADP binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7pmq, PDBe:7pmq, PDBj:7pmq
PDBsum7pmq
PubMed37221012
UniProtP21693|DBPA_ECOLI ATP-dependent RNA helicase DbpA (Gene Name=dbpA)

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