Structure of PDB 7pmf Chain C Binding Site BS01
Receptor Information
>7pmf Chain C (length=372) Species:
9986
(Oryctolagus cuniculus) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
ETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSY
VGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPT
LLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVL
DSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTT
AEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNE
RFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGT
TMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQ
QMWITKQEYDEAGPSIVHRKCF
Ligand information
>7pmf Chain H (length=7) Species:
67723
(Amanita phalloides) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
WLATCPA
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
7pmf
High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism.
Resolution
3.4 Å
Binding residue
(original residue number in PDB)
E72 I75 P112
Binding residue
(residue number reindexed from 1)
E69 I72 P109
Enzymatic activity
Enzyme Commision number
3.6.4.-
Gene Ontology
Molecular Function
GO:0000287
magnesium ion binding
GO:0003785
actin monomer binding
GO:0005509
calcium ion binding
GO:0005515
protein binding
GO:0005523
tropomyosin binding
GO:0005524
ATP binding
GO:0016787
hydrolase activity
GO:0019904
protein domain specific binding
GO:0031013
troponin I binding
GO:0031432
titin binding
GO:0032036
myosin heavy chain binding
GO:0042802
identical protein binding
GO:0048306
calcium-dependent protein binding
GO:0140660
cytoskeletal motor activator activity
Biological Process
GO:0010628
positive regulation of gene expression
GO:0030041
actin filament polymerization
GO:0030240
skeletal muscle thin filament assembly
GO:0048741
skeletal muscle fiber development
GO:0051017
actin filament bundle assembly
GO:0090131
mesenchyme migration
Cellular Component
GO:0001725
stress fiber
GO:0005737
cytoplasm
GO:0005856
cytoskeleton
GO:0005865
striated muscle thin filament
GO:0005884
actin filament
GO:0030027
lamellipodium
GO:0030175
filopodium
GO:0031941
filamentous actin
GO:0032432
actin filament bundle
GO:0044297
cell body
GO:0098723
skeletal muscle myofibril
View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB
RCSB:7pmf
,
PDBe:7pmf
,
PDBj:7pmf
PDBsum
7pmf
PubMed
34812732
UniProt
P68135
|ACTS_RABIT Actin, alpha skeletal muscle (Gene Name=ACTA1)
[
Back to BioLiP
]