Structure of PDB 7p8n Chain C Binding Site BS01

Receptor Information
>7p8n Chain C (length=156) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HFEKVEEILKKYGYKRENLIKILLEIQEIYRYLPEDVINYVSTAMGIPPA
KIYGVATFYAQFSLKPKGKYTIMVCDGTACHMAGSPEVLKAIEEETGLTP
GNVTEDLMFSLDQVGCLGACALAPVMVINGEVYGNLTADKVKEILRKIKE
KERESA
Ligand information
Ligand IDFES
InChIInChI=1S/2Fe.2S
InChIKeyNIXDOXVAJZFRNF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04[Fe]1S[Fe]S1
CACTVS 3.341
OpenEye OEToolkits 1.5.0		S1[Fe]S[Fe]1
FormulaFe2 S2
NameFE2/S2 (INORGANIC) CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain7p8n Chain C Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7p8n Structural insight on the mechanism of an electron-bifurcating [FeFe] hydrogenase.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		C78 G80 C83 C119 L120 A122 C123
Binding residue
(residue number reindexed from 1)		C75 G77 C80 C116 L117 A119 C120
Annotation score3
Enzymatic activity
Enzyme Commision number 1.12.1.4: hydrogenase (NAD(+), ferredoxin).
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:7p8n, PDBe:7p8n, PDBj:7p8n
PDBsum7p8n
PubMed36018003
UniProtO52681|HYDC_THEMA Bifurcating [FeFe] hydrogenase gamma subunit (Gene Name=hydC)

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