Structure of PDB 7p4b Chain C Binding Site BS01

Receptor Information
>7p4b Chain C (length=276) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAP
WMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG
CELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDA
SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPEPVTLRWKP
Ligand information
>7p4b Chain Q (length=9) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
IMYNYPAML
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7p4b Primary and secondary functions of HLA-E are determined by stability and conformation of the peptide-bound complexes.
Resolution1.72 Å
Binding residue
(original residue number in PDB)
Y7 R62 E63 S66 A67 T70 N77 Y84 W97 S143 K146 E152 Q156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 R62 E63 S66 A67 T70 N77 Y84 W97 S143 K146 E152 Q156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7p4b, PDBe:7p4b, PDBj:7p4b
PDBsum7p4b
PubMed35705051
UniProtP13747|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)

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