Structure of PDB 7n06 Chain C Binding Site BS01
Receptor Information
>7n06 Chain C (length=347) Species:
2697049
(Severe acute respiratory syndrome coronavirus 2) [
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EMSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTT
LPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHIST
IGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSV
KGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSR
NLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGL
HLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLL
LDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKL
Ligand information
>7n06 Chain I (length=3) [
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aua
...
Receptor-Ligand Complex Structure
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PDB
7n06
Characterization of SARS2 Nsp15 nuclease activity reveals it's mad about U.
Resolution
2.2 Å
Binding residue
(original residue number in PDB)
H235 Q245 G247 G248 H250 W333 E340 T341 Y343
Binding residue
(residue number reindexed from 1)
H236 Q246 G248 G249 H251 W334 E341 T342 Y344
Enzymatic activity
Enzyme Commision number
2.1.1.56
: mRNA (guanine-N(7))-methyltransferase.
2.1.1.57
: methyltransferase cap1.
2.7.7.48
: RNA-directed RNA polymerase.
2.7.7.50
: mRNA guanylyltransferase.
3.1.13.-
3.4.19.12
: ubiquitinyl hydrolase 1.
3.4.22.-
3.4.22.69
: SARS coronavirus main proteinase.
3.6.4.12
: DNA helicase.
3.6.4.13
: RNA helicase.
4.6.1.-
External links
PDB
RCSB:7n06
,
PDBe:7n06
,
PDBj:7n06
PDBsum
7n06
PubMed
34403466
UniProt
P0DTD1
|R1AB_SARS2 Replicase polyprotein 1ab (Gene Name=rep)
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