Structure of PDB 7mi9 Chain C Binding Site BS01

Receptor Information
>7mi9 Chain C (length=339) Species: 243231 (Geobacter sulfurreducens PCA) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RGLPLYVQSPKAYVRKDGDCLVIEEERVRVAEARLGETSQVALFGNATLT
TAALHECLRREIPVTWLSYGGWFMGHTVSTGHRNVETRTYQYQRSFDPET
CLNLARRWIVAKIANCRTLLRRNWRGEGDEAKAPPGLLMSLQDDMRHAMR
APSLEVLLGIEGASAGRYFQHFSRMLRGGDGEGMGFDFTTRNRRPPKDPV
NALLSFAYAMLTREWTVALAAVGLDPYRGFYHQPRFGRPALALDMMEPFR
PLIADSTVLMAINNGEIRTGDFVRSAGGCNLTDSARKRFIAGFERRMEQE
VTHPIFKYTISYRRLLEVQARLLTRYLSGEIPAYPNFVT
Ligand information
>7mi9 Chain G (length=80) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aggacaacgttacggacggcacagcctttttgcttcaatgaggccggggc
atcatggccccggaatacggctcttttccg
Receptor-Ligand Complex Structure
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PDB7mi9 Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas.
Resolution3.89 Å
Binding residue
(original residue number in PDB)		K526 Y527
Binding residue
(residue number reindexed from 1)		K307 Y308
Enzymatic activity
Enzyme Commision number 3.1.-.-
3.1.12.1: 5' to 3' exodeoxyribonuclease (nucleoside 3'-phosphate-forming).
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0004527 exonuclease activity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:7mi9, PDBe:7mi9, PDBj:7mi9
PDBsum7mi9
PubMed34588691
UniProtQ74H36|CS4F1_GEOSL CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion (Gene Name=cas4-cas1)

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