Structure of PDB 7m5b Chain C Binding Site BS01

Receptor Information
>7m5b Chain C (length=160) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SASEEQVAQDTEEVFRSYVFYRHQQEQEAPADPEMVTLPLQPSSTMGQVG
RQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINW
GRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARWIAQRG
GWVAALNLCN
Ligand information
>7m5b Chain B (length=25) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
EDIIRNIARHLAQMGDSMDRSWGGC
Receptor-Ligand Complex Structure
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PDB7m5b Structural basis of BAK activation in mitochondrial apoptosis initiation.
Resolution1.85 Å
Binding residue
(original residue number in PDB)		Y89 E92
Binding residue
(residue number reindexed from 1)		Y64 E67
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:7m5b, PDBe:7m5b, PDBj:7m5b
PDBsum7m5b
PubMed35017502
UniProtQ16611|BAK_HUMAN Bcl-2 homologous antagonist/killer (Gene Name=BAK1)

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