Structure of PDB 7lz0 Chain C Binding Site BS01

Receptor Information
>7lz0 Chain C (length=252) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSAMGSKPLRIGVPNRVSYTDYVSKDKNPPGVRGYCIDVFEAAIELLPYP
VPRTYILYGDGKRNPSYDNLVNEVVADNFDVAVGDITIVTNRTRYVDFTQ
PFIESGLVVVAPVKEAGTIEGIDSLVTSNEPIGVQDGTFARNYLINELNI
LPSRIVPLKDEEQYLSALQRGPNAGGVAAIVDELPYIEVLLTNSNCKFRT
VGQEFTRTGWGFAFQRDSPLAVDMSTAILQLSEEGELEKIHRKWLNYKHE
CS
Ligand information
Ligand IDGLU
InChIInChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
InChIKeyWHUUTDBJXJRKMK-VKHMYHEASA-N
SMILES
SoftwareSMILES
ACDLabs 12.01O=C(O)C(N)CCC(=O)O
OpenEye OEToolkits 1.7.0C(CC(=O)O)C(C(=O)O)N
OpenEye OEToolkits 1.7.0C(CC(=O)O)[C@@H](C(=O)O)N
CACTVS 3.370N[C@@H](CCC(O)=O)C(O)=O
CACTVS 3.370N[CH](CCC(O)=O)C(O)=O
FormulaC5 H9 N O4
NameGLUTAMIC ACID
ChEMBLCHEMBL575060
DrugBankDB00142
ZINCZINC000001482113
PDB chain7lz0 Chain C Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7lz0 Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4.
Resolution2.29 Å
Binding residue
(original residue number in PDB)		R16 N64 Y67 T87 R92 Q135 D136 T138 F139 E183 Y186
Binding residue
(residue number reindexed from 1)		R16 N64 Y67 T87 R92 Q135 D136 T138 F139 E183 Y186
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:7lz0, PDBe:7lz0, PDBj:7lz0
PDBsum7lz0
PubMed34161757
UniProtQ8GXJ4|GLR34_ARATH Glutamate receptor 3.4 (Gene Name=GLR3.4)

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