Structure of PDB 7lsk Chain C Binding Site BS01 |
| >7lsk Chain C (length=554) Species: 11676 (Human immunodeficiency virus 1)
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PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKI
GPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGL
KKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLP
QGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRT
KIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKD
SWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLK
TGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWET
WWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRET
KLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQ
YALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDK
LVSA |
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| PDB | 7lsk Structural basis of HIV inhibition by L-nucleosides: Opportunities for drug development and repurposing. |
| Resolution | 2.7 Å |
Binding residue
(original residue number in PDB) | W24 F61 L74 D76 R78 E89 I94 G152 W153 K154 P157 Y183 D185 D186 M230 G231 N255 Q258 K259 G262 K263 W266 S280 R284 G285 L289 K353 R358 G359 H361 R448 T473 Q475 K476 Y501 |
Binding residue
(residue number reindexed from 1) | W24 F61 L74 D76 R78 E89 I94 G152 W153 K154 P157 Y183 D185 D186 M230 G231 N255 Q258 K259 G262 K263 W266 S280 R284 G285 L289 K353 R358 G359 H361 R448 T473 Q475 K476 Y501 |
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