Structure of PDB 7lmk Chain C Binding Site BS01

Receptor Information
>7lmk Chain C (length=156) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NRISWVGDAVKTDGKKSYYKKVCIDSETLEVGDCVSVIPDDSSKPLYLAR
VTALWEDSSNGQMFHAHWFCAGTDTVLGATSDPLELFLVDECEDMQLSYI
HSKVQVIYKAPSGAGSATYFYQLWYDQDYARFESPPKTQPTEDNKYKFCA
SCARLA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7lmk DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation.
Resolution2.647 Å
Binding residue
(original residue number in PDB)		I763 D765 Y772 W793 F794 E816 E818 D819 Y824
Binding residue
(residue number reindexed from 1)		I38 D40 Y47 W68 F69 E91 E93 D94 Y99
Enzymatic activity
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
Gene Ontology
Molecular Function
GO:0003682 chromatin binding

View graph for
Molecular Function
External links
PDB RCSB:7lmk, PDBe:7lmk, PDBj:7lmk
PDBsum7lmk
PubMed33941775
UniProtQ24K09|DNMT1_BOVIN DNA (cytosine-5)-methyltransferase 1 (Gene Name=DNMT1)

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