Structure of PDB 7l6n Chain C Binding Site BS01

Receptor Information
>7l6n Chain C (length=675) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QALQKYSTDLTARAREGKLDPVIGRDNEIRRVVQVLSRRTKNNPVLIGEP
GVGKTAIVEGLAQRIVAGDVPESLRDKTIVALDLGSMVAGSKYRGEFEER
LKAVLDDIKNSAGQIITFIDELHTIVGAGATAMDAGNMIKPMLARGELRL
VGATTLDEYRKHIEKDAALERRFQQVYVGEPSVEDTIGILRGLKDRYEVH
HGVRITDSALVAAATLSDRYITARFLPDKAIDLVDEAASRLRMEIDSRPV
EIDEVERLVRRLEIEEMALSKEEDEASAERLAKLRSELADQKEKLAELTT
RWQNEKNAIEIVRDLKEQLEALRGESERAERDGDLAKAAELRYGRIPEVE
KKLDAALPQKEEVGPDDIADVVSAWTGIPAGRLLEGETAKLLRMEDELGK
RVIGQKAAVTAVSDAVRRSRAGVSDPNRPTGAFMFLGPTGVGKTELAKAL
ADFLFDDERAMVRIDMSEYGEKHTVARLIGAPPGYVGYEAGGQLTEAVRR
RPYTVVLFDEIEKAHPDVFDVLLQVLDEGRLTDGHGRTVDFRNTILILTS
NLGSGGSAEQVLAAVRATFKPEFINRLDDVLIFEGLNPEELVRIVDIQLA
QLGKRLAQRRLQLQVSLPAKRWLAQRGFDPVYGARPLRRLVQQAIGDQLA
KMLLAGQVHDGDTVPVNVSPDADSL
Ligand information
>7l6n Chain N (length=26) Species: 1773 (Mycobacterium tuberculosis) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AAAAAAAAAAAAAAAAAAAAAAAAAA
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7l6n Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system.
Resolution7.0 Å
Binding residue
(original residue number in PDB)		K250 Y251 G654 Y655 V656
Binding residue
(residue number reindexed from 1)		K92 Y93 G484 Y485 V486
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0009408 response to heat
GO:0034605 cellular response to heat
GO:0042026 protein refolding
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7l6n, PDBe:7l6n, PDBj:7l6n
PDBsum7l6n
PubMed34038719
UniProtP9WPD1|CLPB_MYCTU Chaperone protein ClpB (Gene Name=clpB)

[Back to BioLiP]