Structure of PDB 7kc6 Chain C Binding Site BS01

Receptor Information

>7kc6 Chain C (length=184) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GSGNVDLVFLFDGSMSLQPDEFQKILDFMKDVMKKLSNTSYQFAAVQFST
SYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELG
ARPDATKVLIIITDGEATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLH
KFASKPASEFVKILDTFEKLKDLFTELQKKIYVI

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

7kc6 Chain C Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7kc6 Divergent conformational dynamics controls allosteric ligand accessibility across evolutionarily related I-domain-containing integrins
Resolution	1.85 Å
Binding residue (original residue number in PDB)	D137 S139 T206 D239 G240
Binding residue (residue number reindexed from 1)	D12 S14 T81 D114 G115
Annotation score	4

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:7kc6, PDBe:7kc6, PDBj:7kc6
PDBsum	7kc6
PubMed
UniProt	P20701\|ITAL_HUMAN Integrin alpha-L (Gene Name=ITGAL)

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