Structure of PDB 7kc5 Chain C Binding Site BS01

Receptor Information
>7kc5 Chain C (length=182) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GNVDLVFLFDGSMSLQPDEFQKILDFMKDVMKKLSNTSYQFAAVQFSTSY
KTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGAR
PDATKVLIIITDGEATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLHKF
ASKPASEFVKILDTFEKLKDLFTELQKKIYVI
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7kc5 Chain C Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7kc5 Divergent conformational dynamics controls allosteric ligand accessibility across evolutionarily related I-domain-containing integrins
Resolution1.86 Å
Binding residue
(original residue number in PDB)		D137 S139 M140 T206 D239
Binding residue
(residue number reindexed from 1)		D10 S12 M13 T79 D112
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7kc5, PDBe:7kc5, PDBj:7kc5
PDBsum7kc5
PubMed
UniProtP20701|ITAL_HUMAN Integrin alpha-L (Gene Name=ITGAL)

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