Structure of PDB 7jk5 Chain C Binding Site BS01

Receptor Information
>7jk5 Chain C (length=590) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKGCFVYKNGATRSLLGKEVVQQPFYEEYRKAWNQINDHIADLQHRSYAR
TLEQLVDFVVGQAEREVLPTAALLTGINQPDHLSQFTALTQRLHAQRAAM
VCVLQSRDCATLKAAVETLVFGLVEDNAEVERLRRSQCTMKQLKSWYTNN
FDSERRQLVVILPDFECFNASVLQDLILILSAHCGSLPFVLVLGVATAMT
AVHGTLPYHVSSKIRLRVFQTQAAPTGLNEVLDKVLLSPKYAFHLSGKTF
KFLTHIFLYYDFSIHGFIQGFKYCLMEHFFGGNAFALCTDYSKALGRIKQ
LTHEDMETIRRLPSFRPYVEQIIIAVLTDDDYLKKKLPQLLRDCLLHFLL
FRCSLEFLTELVGDLPRCPLGKLRRELYVNCLNRAIISTPEYKECLQMLS
FLSKDEFVAKVNRALERTEQFLVEEIAPLELGEACTAVLRPKLEAIRLAV
DEVVKGRALQKTLQLIETQIVQDHLRALQDAPPIHELFVFSDIATVRRNI
IGAPRAALHTALNNPHFYMQCKCCETLPDLSVVYKLHLECGRMINLFDWL
QAFRSVVPQIQARFTRAVAELQFLGYIKMSKRKTDHATRL
Ligand information
>7jk5 Chain F (length=14) Species: 7227 (Drosophila melanogaster) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
DYEIWKARMLAKAQ
Receptor-Ligand Complex Structure
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PDB7jk5 Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		R358 R363 V366 E367 I375 I376 L379 T380
Binding residue
(residue number reindexed from 1)		R311 R316 V319 E320 I323 I324 L327 T328
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003688 DNA replication origin binding
GO:0005515 protein binding
GO:0043021 ribonucleoprotein complex binding
Biological Process
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
GO:0007611 learning or memory
GO:0007612 learning
GO:0008355 olfactory learning
GO:0030536 larval feeding behavior
GO:1903688 positive regulation of border follicle cell migration
Cellular Component
GO:0005634 nucleus
GO:0005643 nuclear pore
GO:0005656 nuclear pre-replicative complex
GO:0005664 nuclear origin of replication recognition complex
GO:0031261 DNA replication preinitiation complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7jk5, PDBe:7jk5, PDBj:7jk5
PDBsum7jk5
PubMed32848132
UniProtQ7K2L1

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