Structure of PDB 7jk4 Chain C Binding Site BS01

Receptor Information
>7jk4 Chain C (length=612) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDPTISVSKGCFVYKNGATRSLLGKEVVQQPFYEEYRKAWNQINDHIADL
QHRSYARTLEQLVDFVVGQAEREVLPTAALLTGINQPDHLSQFTALTQRL
HAQRAAMVCVLQSRDCATLKAAVETLVFGLVEDNAEVERLRRSQCTMKQL
KSWYTNNFDSERRQLVVILPDFECFNASVLQDLILILSAHCGSLPFVLVL
GVATAMTAVHGTLPYHVSSKIRLRVFQTQAAPTGLNEVLDKVLLSPKYAF
HLSGKTFKFLTHIFLYYDFSIHGFIQGFKYCLMEHFFGGNAFALCTDYSK
ALGRIKQLTHEDMETIRRLPSFRPYVEQICKRIIAVLTDDDYLKKKLPQL
LRDCLLHFLLFRCSLEFLTELVGDLPRCPLGKLRRELYVNCLNRAIISTP
EYKECLQMLSFLSKDEFVAKVNRALERTEQFLVEEIAPLELGEACTAVLR
PKLEAIRLAVDEVVKAGRALQKTLQLIETQIVQDHLRALQDAPPIHELFV
FSDIATVRRNIIGAPRAALHTALNNPHFYMQCKCCELQDQSLLVGTLPDL
SVVYKLHLECGRMINLFDWLQAFRSVVPQIQARFTRAVAELQFLGYIKMS
KRKTDHATRLTW
Ligand information
>7jk4 Chain F (length=17) Species: 7227 (Drosophila melanogaster) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
EDYEIWKARMLAKAQAK
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7jk4 Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		E354 R358 R363 V366 I375
Binding residue
(residue number reindexed from 1)		E314 R318 R323 V326 I333
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003688 DNA replication origin binding
GO:0005515 protein binding
GO:0043021 ribonucleoprotein complex binding
Biological Process
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
GO:0007611 learning or memory
GO:0007612 learning
GO:0008355 olfactory learning
GO:0030536 larval feeding behavior
GO:1903688 positive regulation of border follicle cell migration
Cellular Component
GO:0005634 nucleus
GO:0005643 nuclear pore
GO:0005656 nuclear pre-replicative complex
GO:0005664 nuclear origin of replication recognition complex
GO:0031261 DNA replication preinitiation complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7jk4, PDBe:7jk4, PDBj:7jk4
PDBsum7jk4
PubMed32848132
UniProtQ7K2L1

[Back to BioLiP]