Structure of PDB 7jk3 Chain C Binding Site BS01

Receptor Information
>7jk3 Chain C (length=614) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDPTISVSKGCFVYKNGATRSLLGKEVVQQPFYEEYRKAWNQINDHIADL
QHRSYARTLEQLVDFVVGQAEREVLPTAALLTGINQPDHLSQFTALTQRL
HAQRAAMVCVLQSRDCATLKAAVETLVFGLVEDNAEVERLRRSQCTMKQL
KSWYTNNFDSERRQLVVILPDFECFNASVLQDLILILSAHCGSLPFVLVL
GVATAMTAVHGTLPYHVSSKIRLRVFQTQAAPTGLNEVLDKVLLSPKYAF
HLSGKTFKFLTHIFLYYDFSIHGFIQGFKYCLMEHFFGGNAFALCTDYSK
ALGRIKQLTHEDMETIRRLPSFRPYVEQINDCKRIIAVLTDDDYLKKKLP
QLLRDCLLHFLLFRCSLEFLTELVGDLPRCPLGKLRRELYVNCLNRAIIS
TPEYKECLQMLSFLSKDEFVAKVNRALERTEQFLVEEIAPLELGEACTAV
LRPKLEAIRLAVDEVVKAGRALQKTLQLIETQIVQDHLRALQDAPPIHEL
FVFSDIATVRRNIIGAPRAALHTALNNPHFYMQCKCCELQDQSLLVGTLP
DLSVVYKLHLECGRMINLFDWLQAFRSVVPQIQARFTRAVAELQFLGYIK
MSKRKTDHATRLTW
Ligand information
>7jk3 Chain F (length=17) Species: 7227 (Drosophila melanogaster) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
EDYEIWKARMLAKAQAK
Receptor-Ligand Complex Structure
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PDB7jk3 Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		R358 R363 V366 I376
Binding residue
(residue number reindexed from 1)		R318 R323 V326 I336
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003688 DNA replication origin binding
GO:0005515 protein binding
GO:0043021 ribonucleoprotein complex binding
Biological Process
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
GO:0007611 learning or memory
GO:0007612 learning
GO:0008355 olfactory learning
GO:0030536 larval feeding behavior
GO:1903688 positive regulation of border follicle cell migration
Cellular Component
GO:0005634 nucleus
GO:0005643 nuclear pore
GO:0005656 nuclear pre-replicative complex
GO:0005664 nuclear origin of replication recognition complex
GO:0031261 DNA replication preinitiation complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7jk3, PDBe:7jk3, PDBj:7jk3
PDBsum7jk3
PubMed32848132
UniProtQ7K2L1

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