Structure of PDB 7jgs Chain C Binding Site BS01

Receptor Information
>7jgs Chain C (length=614) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDPTISVSKGCFVYKNGATRSLLGKEVVQQPFYEEYRKAWNQINDHIADL
QHRSYARTLEQLVDFVVGQAEREVLPTAALLTGINQPDHLSQFTALTQRL
HAQRAAMVCVLQSRDCATLKAAVETLVFGLVEDNAEVERLRRSQCTMKQL
KSWYTNNFDSERRQLVVILPDFECFNASVLQDLILILSAHCGSLPFVLVL
GVATAMTAVHGTLPYHVSSKIRLRVFQTQAAPTGLNEVLDKVLLSPKYAF
HLSGKTFKFLTHIFLYYDFSIHGFIQGFKYCLMEHFFGGNAFALCTDYSK
ALGRIKQLTHEDMETIRRLPSFRPYVEQINDCKRIIAVLTDDDYLKKKLP
QLLRDCLLHFLLFRCSLEFLTELVGDLPRCPLGKLRRELYVNCLNRAIIS
TPEYKECLQMLSFLSKDEFVAKVNRALERTEQFLVEEIAPLELGEACTAV
LRPKLEAIRLAVDEVVKAGRALQKTLQLIETQIVQDHLRALQDAPPIHEL
FVFSDIATVRRNIIGAPRAALHTALNNPHFYMQCKCCELQDQSLLVGTLP
DLSVVYKLHLECGRMINLFDWLQAFRSVVPQIQARFTRAVAELQFLGYIK
MSKRKTDHATRLTW
Ligand information
>7jgs Chain F (length=17) Species: 7227 (Drosophila melanogaster) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
EDYEIWKARMLAKAQAK
Receptor-Ligand Complex Structure
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PDB7jgs Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		E354 R357 R358 R363 V366 C372 I376 L379
Binding residue
(residue number reindexed from 1)		E314 R317 R318 R323 V326 C332 I336 L339
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003688 DNA replication origin binding
GO:0005515 protein binding
GO:0043021 ribonucleoprotein complex binding
Biological Process
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
GO:0007611 learning or memory
GO:0007612 learning
GO:0008355 olfactory learning
GO:0030536 larval feeding behavior
GO:1903688 positive regulation of border follicle cell migration
Cellular Component
GO:0005634 nucleus
GO:0005643 nuclear pore
GO:0005656 nuclear pre-replicative complex
GO:0005664 nuclear origin of replication recognition complex
GO:0031261 DNA replication preinitiation complex

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7jgs, PDBe:7jgs, PDBj:7jgs
PDBsum7jgs
PubMed32848132
UniProtQ7K2L1

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