Structure of PDB 7jgr Chain C Binding Site BS01

Receptor Information
>7jgr Chain C (length=612) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDPTISVSKGCFVYKNGATRSLLGKEVVQQPFYEEYRKAWNQINDHIADL
QHRSYARTLEQLVDFVVGQAEREVLPTAALLTGINQPDHLSQFTALTQRL
HAQRAAMVCVLQSRDCATLKAAVETLVFGLVEDNAEVERLRRSQCTMKQL
KSWYTNNFDSERRQLVVILPDFECFNASVLQDLILILSAHCGSLPFVLVL
GVATAMTAVHGTLPYHVSSKIRLRVFQTQAAPTGLNEVLDKVLLSPKYAF
HLSGKTFKFLTHIFLYYDFSIHGFIQGFKYCLMEHFFGGNAFALCTDYSK
ALGRIKQLTHEDMETIRRLPSFRPYVEQICKRIIAVLTDDDYLKKKLPQL
LRDCLLHFLLFRCSLEFLTELVGDLPRCPLGKLRRELYVNCLNRAIISTP
EYKECLQMLSFLSKDEFVAKVNRALERTEQFLVEEIAPLELGEACTAVLR
PKLEAIRLAVDEVVKAGRALQKTLQLIETQIVQDHLRALQDAPPIHELFV
FSDIATVRRNIIGAPRAALHTALNNPHFYMQCKCCELQDQSLLVGTLPDL
SVVYKLHLECGRMINLFDWLQAFRSVVPQIQARFTRAVAELQFLGYIKMS
KRKTDHATRLTW
Ligand information
>7jgr Chain F (length=17) Species: 7227 (Drosophila melanogaster) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
EDYEIWKARMLAKAQAK
Receptor-Ligand Complex Structure
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PDB7jgr Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		R357 R358 R363 V366 I375 L379
Binding residue
(residue number reindexed from 1)		R317 R318 R323 V326 I333 L337
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003688 DNA replication origin binding
GO:0005515 protein binding
GO:0043021 ribonucleoprotein complex binding
Biological Process
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
GO:0007611 learning or memory
GO:0007612 learning
GO:0008355 olfactory learning
GO:0030536 larval feeding behavior
GO:1903688 positive regulation of border follicle cell migration
Cellular Component
GO:0005634 nucleus
GO:0005643 nuclear pore
GO:0005656 nuclear pre-replicative complex
GO:0005664 nuclear origin of replication recognition complex
GO:0031261 DNA replication preinitiation complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7jgr, PDBe:7jgr, PDBj:7jgr
PDBsum7jgr
PubMed32848132
UniProtQ7K2L1

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