Structure of PDB 7fcb Chain C Binding Site BS01

Receptor Information
>7fcb Chain C (length=273) Species: 5065 (Aspergillus sp.) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PQLHYVPYDTPVEDVMRILKESGTLVIRNFLDQNTVQKVQDEVDDYVRNW
KTKQPSNLSLMSKTYRCEVLNHPWMHAICERMFGPTYGDYWFNGGSILHL
EPGENTQPIHQDHVFYQISKWRRPTDPDLTINFTMALTEFTVENGGTRVC
PGSHLWENGHASPAEEDMVPVLMQPGDALILPGSMWHSAGANRTSEYRRG
FATSFHPCHFTPIESHHHLPREMVEEMTPLVQKMLGFRTLNLHNNVKVWK
AGEGNLEDATGLKSVAAKLAAAL
Ligand information
Ligand IDFE2
InChIInChI=1S/Fe/q+2
InChIKeyCWYNVVGOOAEACU-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Fe+2]
CACTVS 3.341[Fe++]
FormulaFe
NameFE (II) ION
ChEMBL
DrugBankDB14510
ZINC
PDB chain7fcb Chain C Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7fcb Molecular insights into the unusually promiscuous and catalytically versatile Fe(II)/ alpha-ketoglutarate-dependent oxygenase SptF.
Resolution1.4 Å
Binding residue
(original residue number in PDB)		H119 D121 H196
Binding residue
(residue number reindexed from 1)		H110 D112 H187
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity

View graph for
Molecular Function
External links
PDB RCSB:7fcb, PDBe:7fcb, PDBj:7fcb
PDBsum7fcb
PubMed35013177
UniProtA0A6J4CX17

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