Structure of PDB 7eys Chain C Binding Site BS01

Receptor Information
>7eys Chain C (length=277) Species: 5065 (Aspergillus sp.) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PQLHYVPYDTPVEDVMRILKESGTLVIRNFLDQNTVQKVQDEVDDYVRNW
NPGPKYNHDIKNVGSKTKQPSNLSLMSKTYRCEVLNHPWMHAICERMFGP
TYGDYWFNGGSILHLEPGENTQPIHQDHVFYQISKWRRPTDPDLTINFTM
ALTEFTVENGGTRVCPGSHLWENGHASPAEEDMVPVLMQPGDALILPGSM
WHSAGANRTSEYRRGFATSFHPCHFTPIESHHHLPREMVEEMTPLVQKML
GFRTLNLHNNVKVWKAGEGNLEDATGL
Ligand information
Ligand IDAKG
InChIInChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)
InChIKeyKPGXRSRHYNQIFN-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O=C(O)C(=O)CCC(=O)O
OpenEye OEToolkits 1.7.6C(CC(=O)O)C(=O)C(=O)O
CACTVS 3.385OC(=O)CCC(=O)C(O)=O
FormulaC5 H6 O5
Name2-OXOGLUTARIC ACID
ChEMBLCHEMBL1686
DrugBankDB08845
ZINCZINC000001532519
PDB chain7eys Chain C Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7eys Molecular insights into the unusually promiscuous and catalytically versatile Fe(II)/ alpha-ketoglutarate-dependent oxygenase SptF.
Resolution1.95 Å
Binding residue
(original residue number in PDB)		Q125 H128 T165 H205 A207 R216
Binding residue
(residue number reindexed from 1)		Q122 H125 T162 H202 A204 R213
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity

View graph for
Molecular Function
External links
PDB RCSB:7eys, PDBe:7eys, PDBj:7eys
PDBsum7eys
PubMed35013177
UniProtA0A6J4CX17

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