Structure of PDB 7eu0 Chain C Binding Site BS01

Receptor Information
>7eu0 Chain C (length=291) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TYQRFPKIKIRELKDDYAKFELRETDVSMANALRRVMISEVPTVAIDLVE
IEVNSSVLNDEFIAHRLGLIPLTSERAMSMRFSRDCDACDGDGQCEFCSV
EFRLSSKCVTDQTLDVTSRDLYSADPTVTPVDFHKGIIIVKLRRGQELKL
RAIARKGIGKDHAKWSPAATVTFMYEPDIIINEDMMDTLSDEEKIDLIES
SPTKVFGMDPVTRQVVVVDPEAYTYDEEVIKKAEAMGKPGLIEISPKDDS
FIFTVESTGAVKASQLVLNAIDLLKQKLDAVRLSDDTVEAD
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7eu0 Chain C Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7eu0 Pol IV and RDR2: A two-RNA-polymerase machine that produces double-stranded RNA.
Resolution3.16 Å
Binding residue
(original residue number in PDB)
C93 C99 C102
Binding residue
(residue number reindexed from 1)
C89 C95 C98
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0005515 protein binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006351 DNA-templated transcription
GO:0010374 stomatal complex development
GO:0010375 stomatal complex patterning
Cellular Component
GO:0000418 RNA polymerase IV complex
GO:0000419 RNA polymerase V complex
GO:0000428 DNA-directed RNA polymerase complex
GO:0005634 nucleus
GO:0005665 RNA polymerase II, core complex
GO:0005730 nucleolus
GO:0005737 cytoplasm

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7eu0, PDBe:7eu0, PDBj:7eu0
PDBsum7eu0
PubMed34941388
UniProtQ39211|NRPB3_ARATH DNA-directed RNA polymerases II, IV and V subunit 3 (Gene Name=NRPB3)

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