Structure of PDB 7eqx Chain C Binding Site BS01

Receptor Information
>7eqx Chain C (length=299) Species: 7159 (Aedes aegypti) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DVSTSYLRHNEINEYLQTLSQKYPSLVSVEEAGTSYEGRSIKTITINKKP
GNAVVFLDAGIHAREWIAPATALYAIEQLVEHSSENQEVLSNLTWVIMPV
VNPDGYEFSHETDRFWRKTRKPTGKSCKGTDGNRNFDYHWGEVGASTQAC
ADTFRGETAFSEPETRAVRDAVMKLKGSCKFYLSLHSYGNYILYPWGWTS
KLPETWEAIDEVAQAGAEAIKQSTGSRYTVGSSTNVLYAAAGGSDDWAFA
VAEVPISITMELPGGGNGGFNPPPSSIEKIVNESWVGIKAMALKVAQMF
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7eqx Chain C Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7eqx Structure of Aedes aegypti procarboxypeptidase B1 and its binding with Dengue virus for controlling infection.
Resolution2.08 Å
Binding residue
(original residue number in PDB)		H68 E71 H192
Binding residue
(residue number reindexed from 1)		H62 E65 H186
Annotation score1
Enzymatic activity
Enzyme Commision number 3.4.17.2: carboxypeptidase B.
Gene Ontology
Molecular Function
GO:0004181 metallocarboxypeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7eqx, PDBe:7eqx, PDBj:7eqx
PDBsum7eqx
PubMed34750241
UniProtA0A1S4F020|CBPB1_AEDAE Carboxypeptidase B1 (Gene Name=CPB1)

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