Structure of PDB 7ebr Chain C Binding Site BS01

Receptor Information
>7ebr Chain C (length=232) Species: 42789 (enterovirus D68) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VLQLKLGNSAIVTQEAANYCCAYGEWPNYLPDHEAVAIDKPTQPETATDR
FYTLKSVKWETGSTGWWWKLPDALNNIGMFGQNVQHHYLYRSGFLIHVQC
NATKFHQGALLVVAIPEHQRGAHNTNTSPGFDDIMKGEEGGTFNHPYVLD
DGTSLACATIFPHQWINLRTNNSATIVLPWMNAAPMDFPLRHNQWTLAII
PVVPLGTRTTSSMVPITVSIAPMCCEFNGLRH
Ligand information
>7ebr Chain D (length=28) Species: 42789 (enterovirus D68) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
NFYKDSYAASASKQDFSQDPSKFTEPVV
Receptor-Ligand Complex Structure
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PDB7ebr Functional and structural characterization of a two-MAb cocktail for delayed treatment of enterovirus D68 infections.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		N30 Y31 C33 Y35
Binding residue
(residue number reindexed from 1)		N18 Y19 C21 Y23
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:7ebr, PDBe:7ebr, PDBj:7ebr
PDBsum7ebr
PubMed34006855
UniProtA0A097BW12

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