Structure of PDB 7e1s Chain C Binding Site BS01

Receptor Information
>7e1s Chain C (length=366) Species: 210 (Helicobacter pylori) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HHHMVSTLKPLKIGKHTIKFPIFQGGMGVGISWDELAGNVAKEGALGVIS
AVGTGYYKNMRFVERIVAKKPFEALNFYSKKALNEIFANARKICGNNPLG
ANILYAINDYGRVLRDSCEAGANIIITGAGLPTNMPEFAKDFSDVALIPI
ISSAKALKILCKRWSDRYKRIPDAFIVEGPLSGGHQGFKYEDCFKEEFRL
ENLVPKVVEASKEWGNIPIIAAGGIWDRKDIDTMLSLGASGVQMATRFLG
TKECDAKVYADLLPTLKKEDILLIKSPVGYPARAINTGVIKRIEEGNAPK
IACVSNCVAPCNRGEEAKKVGYCIADGLGRSYLGNREEGLYFTGANGYRV
DKIISVHELIKELTEG
Ligand information
>7e1s Chain D (length=22) Species: 210 (Helicobacter pylori) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
DSLDVVELIMALEEKFGIEIPD
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7e1s Helicobacter pylori FabX contains a [4Fe-4S] cluster essential for unsaturated fatty acid synthesis.
Resolution2.31 Å
Binding residue
(original residue number in PDB)		L128 T130 N131 K152 I156 K159 R160 R164
Binding residue
(residue number reindexed from 1)		L131 T133 N134 K155 I159 K162 R163 R167
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0018580 nitronate monooxygenase activity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding

View graph for
Molecular Function
External links
PDB RCSB:7e1s, PDBe:7e1s, PDBj:7e1s
PDBsum7e1s
PubMed34836944
UniProtB5Z7D6

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