Structure of PDB 7dh7 Chain C Binding Site BS01

Receptor Information

>7dh7 Chain C (length=150) Species: 314565 (Xanthomonas campestris pv. campestris str. 8004) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

HVDDANSFVRAVERACSERGLRLTPIRANVLRLIADAGKPVKAYELLDWV
REGKGVGADAPPTVYRALDFLMANGFVHKLESVNAFVACHHPNSAQHSVP
FLICDRCHSAVELEDRDVVSQLEARAKALGFQPQAQTLEVHGLCAKCAAA

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

7dh7 Chain C Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7dh7 Structural basis for zinc-induced activation of a zinc uptake transcriptional regulator.
Resolution	2.2 Å
Binding residue (original residue number in PDB)	C124 C127 C164 C167
Binding residue (residue number reindexed from 1)	C104 C107 C144 C147
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0000976	transcription cis-regulatory region binding
GO:0003677	DNA binding
GO:0003700	DNA-binding transcription factor activity
GO:0008270	zinc ion binding
GO:0046872	metal ion binding

	Biological Process
GO:0006355	regulation of DNA-templated transcription
GO:0045892	negative regulation of DNA-templated transcription
GO:1900376	regulation of secondary metabolite biosynthetic process

	Cellular Component
GO:0005829	cytosol

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Cellular Component

External links

PDB	RCSB:7dh7, PDBe:7dh7, PDBj:7dh7
PDBsum	7dh7
PubMed	34048589
UniProt	Q4UWS5

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