Structure of PDB 7dah Chain C Binding Site BS01

Receptor Information

>7dah Chain C (length=288) Species: 579112 (Vibrio cholerae M66-2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

TQRLRIAIQKKGRLSQECQELLKKCGVKFNIMGERLVVHSLNMPIDLLLV
RDDDIPGLIMDGVVDLGFVGENVLEETRLDRLALNQRNEFTTLRRMDFGG
CRLSIAIEKDAEYRGPQDLNGKRIATTYPQLLKAYMDRQGVDFSTCMLTG
SVEVAPRAGLADAIADLVSTGATLEANGLKEVEVIFESKATLIQRPGAFA
ADKAALIDKLLTRMHGVQQAKESKYIMLHAPVEKLAQIKTLLPGAEDPTV
PLAVHMVSSENLFWETMEQLKALGASSILVLPIEKMME

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

7dah Chain C Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7dah Adenosine triphosphate phosphoribosyltransferase from Vibrio cholerae in complex with ATP and PRPP
Resolution	2.92 Å
Binding residue (original residue number in PDB)	D60 D61
Binding residue (residue number reindexed from 1)	D52 D53
Annotation score	1

Enzymatic activity

Enzyme Commision number

2.4.2.17: ATP phosphoribosyltransferase.

Gene Ontology

	Molecular Function
GO:0000287	magnesium ion binding
GO:0003879	ATP phosphoribosyltransferase activity
GO:0005524	ATP binding
GO:0016757	glycosyltransferase activity
GO:0046872	metal ion binding

	Biological Process
GO:0000105	L-histidine biosynthetic process

	Cellular Component
GO:0005737	cytoplasm

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Cellular Component

External links

PDB	RCSB:7dah, PDBe:7dah, PDBj:7dah
PDBsum	7dah
PubMed
UniProt	Q9KSX4\|HIS1_VIBCH ATP phosphoribosyltransferase (Gene Name=hisG)

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