Structure of PDB 7cxo Chain C Binding Site BS01

Receptor Information
>7cxo Chain C (length=486) Species: 83333,235909,1202714 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KMPAYEFWFVVGSQHLYGDEALAQVEAHAREMVPALQAAVGNAHVLRWKG
VLKDADEIRRLCLEASADDVCAGVIAWMHTFSPAKMWIRGLLALRKPLLH
LHTQFNRDIPWDTIDMDFMNLNQSAHGDREYGFIGARMGVARKVVVGHWE
DPEVRERLAKWMRTAVAFAESRNLKVARFGDNMREVAVTEGDKVGAQIQF
GWSVNGYGIGDLVQYIRDVSEQKVNELLDEYEELYDIVPASIREQARIEL
GLKAFLQDGNFTAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKT
AALLRIMKVMSTGLQGGTSFMEDYTYHFEKGNDLVLGSHMLEVCPSIAAE
EKPILDVQHLGIGGKDDPARLVFDGGEGAAVNASLIDLGHRFRLIVNEVD
AVKPEHDMPKLPVARILWKPRPSLRDSAEAWILAGGAHHTCFSFAVTTEQ
LQDFAEMAGIECVVINEHTSVSSFKNELKWNEVFWR
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain7cxo Chain C Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7cxo Crystal structure of Arabinose isomerase from hyper thermophilic hybrid AI10
Resolution3.2 Å
Binding residue
(original residue number in PDB)		E305 E332 H349 H448 H449
Binding residue
(residue number reindexed from 1)		E295 E322 H339 H438 H439
Annotation score1
Enzymatic activity
Enzyme Commision number 5.3.1.4: L-arabinose isomerase.
Gene Ontology
Molecular Function
GO:0008733 L-arabinose isomerase activity
GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses
Biological Process
GO:0005996 monosaccharide metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7cxo, PDBe:7cxo, PDBj:7cxo
PDBsum7cxo
PubMed
UniProtK0IGW6;
P08202|ARAA_ECOLI L-arabinose isomerase (Gene Name=araA);
Q5KYP7|ARAA_GEOKA L-arabinose isomerase (Gene Name=araA)

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