Structure of PDB 7cmy Chain C Binding Site BS01

Receptor Information

>7cmy Chain C (length=417) Species: 226900 (Bacillus cereus ATCC 14579) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

KNERIEKLQESWELDERWEGITRPYSAEDVIRLRGSIDIEHTLARRGAEK
LWTSLHTEDYINALGALTGNQAMQQVKAGLKAIYLSGWQVAADANLSGHM
YPDQSLYPANSVPAVVKRINQTLQRADQIQHMEGSDDTDYFVPIVADAEA
GFGGQLNVFELMKGMIEAGASGVHFEDQLSSEKKCGHLGGKVLLPTQTAV
RNLISARLAADVMGVPTIIVARTDADAADLITSDIDPVDKAFITGERTPE
GFYRTNAGLDQAIARGLAYAPYADLVWCETSEPNLEDAKRFADAIHKEHP
GKLLAYNCSPSFNWKQKLASFQKEIASYGYKFQFVTLAGFHSLNYGMFEL
ARGYKERGMAAYSELQQAEFAAEKHGYSATRHQREVGTGYFDEVAQVITG
GTSSTTALKGSTEEAQF

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

7cmy Chain C Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7cmy Isocitrate lyase from Bacillus cereus ATCC 14579 in complex with Magnessium ion, glyoxylate, and succinate
Resolution	2.5 Å
Binding residue (original residue number in PDB)	D104 D148 K184
Binding residue (residue number reindexed from 1)	D103 D147 K183
Annotation score	1

Enzymatic activity

Enzyme Commision number

4.1.3.1: isocitrate lyase.

Gene Ontology

	Molecular Function
GO:0003824	catalytic activity
GO:0004451	isocitrate lyase activity
GO:0016829	lyase activity
GO:0046872	metal ion binding

	Biological Process
GO:0019752	carboxylic acid metabolic process

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Molecular Function

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Biological Process

External links

PDB	RCSB:7cmy, PDBe:7cmy, PDBj:7cmy
PDBsum	7cmy
PubMed
UniProt	Q81GQ9

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