Structure of PDB 7cec Chain C Binding Site BS01

Receptor Information
>7cec Chain C (length=574) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VHNASLALSASIGRVRELCAQARGAASKVKVPMKFNGRSGVQLRTPRDLA
DLAAYTALKFYLQGPEDRFVMYMGSRQATGDYMGVSLRDKKVHWVYQLGE
AGPAVLSIDEDIGEQFAAVSLDRTLQFGHMSVTVERQMIQETKGDTVAPG
AEGLLNLRPDDFVFYVGGYPSTFTPPPLLRFPGYRGCIEMDTLNEEVVSL
YNFERTFQLDTAVDRPCARSKSTGDPWLTDGSYLDGTGFARISFDSQIST
TKRFEQELRLVSYSGVLFFLKQQSQFLCLAVQEGSLVLLYDFGAGLKKAV
PLQPPPPLTSASKAIQVFLLGGSRKRVLVRVERATVYSVEQDNDLELADA
YYLGGVPPDQLPPSLRRLFPTGGSVRGCVKGIKALGKYVDLKRLNTTGVS
AGCTADLLVGRAMTFHGHGFLRLALSNVAPLTGNVYSGFGFHSAQDSALL
YYRASPDGLCQVSLQQGRVSLQLLRTEVKTQAGFADGAPHYVAFYSNATG
VWLYVDDQLQQMKPHRGPPEGPPRLLLGGLPESGTIYNFSGCISNVFVQR
LLGPQRVFDLQQNLGSVNVSTGCA
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7cec Chain C Residue 3401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7cec Structural mechanism of laminin recognition by integrin.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		D2793 L2810 E2864 L2866 N2868 D3219
Binding residue
(residue number reindexed from 1)		D81 L98 E152 L154 N156 D507
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Biological Process
External links
PDB RCSB:7cec, PDBe:7cec, PDBj:7cec
PDBsum7cec
PubMed34188035
UniProtO15230|LAMA5_HUMAN Laminin subunit alpha-5 (Gene Name=LAMA5)

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