Structure of PDB 7bu9 Chain C Binding Site BS01

Receptor Information
>7bu9 Chain C (length=205) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VSQPRRNIVGCRIQHGWKEGNGPVTQWKGTVLDQVPVNPSLYLIKYDGFD
CVYGLELNKDERVSALEVLPDRVATSRISDAHLADTMIGKAVEHMFETED
GSKDEWRGMVLARAPVMNTWFYITYEKDPVLYMYQLLDDYKEGDLRIMPD
EPGEVVDSLVGKQVEYAKEDGSKRTGMVIHQVEAKPSVYFIKFDDDFHIY
VYDLV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7bu9 Molecular basis for histone H3 "K4me3-K9me3/2" methylation pattern readout by Spindlin1.
Resolution3.502 Å
Binding residue
(original residue number in PDB)
W62 W72 Y91 F94 D95 C96 F141 E142 W151 D173 Y177 Y179 D184 D189
Binding residue
(residue number reindexed from 1)
W17 W27 Y46 F49 D50 C51 F96 E97 W106 D128 Y132 Y134 D139 D144
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0007276 gamete generation

View graph for
Biological Process
External links
PDB RCSB:7bu9, PDBe:7bu9, PDBj:7bu9
PDBsum7bu9
PubMed32994220
UniProtQ9Y657|SPIN1_HUMAN Spindlin-1 (Gene Name=SPIN1)

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