Structure of PDB 7bq0 Chain C Binding Site BS01

Receptor Information
>7bq0 Chain C (length=271) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMTADLKSLAKRIYEAYLKNFNMNKVKARVILSGKASNNPPFVIHDMETL
CMAEKTLVAKLVANGIQNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGF
ANLDLNDQVTLLKYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSL
RKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGLLNVGHI
EKMQEGIVHVLRLHLQSNHPDDIFLFPKLLQKMADLRQLVTEHAQLVQII
KKTESDAALHPLLQEIYRDMY
Ligand information
Receptor-Ligand Complex Structure
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PDB7bq0 PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates.
Resolution1.771 Å
Binding residue
(original residue number in PDB)		K292 N303 V306 K310 E462 D466
Binding residue
(residue number reindexed from 1)		K95 N106 V109 K113 E265 D269
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7bq0, PDBe:7bq0, PDBj:7bq0
PDBsum7bq0
PubMed33205029
UniProtQ07869|PPARA_HUMAN Peroxisome proliferator-activated receptor alpha (Gene Name=PPARA)

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