Structure of PDB 7afh Chain C Binding Site BS01

Receptor Information
>7afh Chain C (length=211) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLTKELAKAS
VSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQI
NIAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKV
EVSGRLGGAEIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVW
IFKGEILGGMA
Ligand information
>7afh Chain 1 (length=456) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccgcacaagcgguggagcaugugguuuaauucgaugcaacgcgaagaacc
uuaccuggucuugacauccacggaaguuuucagagaugagaaugugccuu
cgggaaccgugagacaggugcugcauggcugucgucagcucguguuguga
aauguuggguuaagucccgcaacgagcgcaacccuuauccuuuguugcca
gcgguccggccgggaacucaaaggagacugccagugauaaacuggaggaa
gguggggaugacgucaagucaucauggcccuuacgaccagggcuacacac
gugcuacaauggcgcauacaaagagaagcgaccucgcgagagcaagcgga
ccucauaaagugcgucguaguccggauuggagucugcaacucgacuccau
gaagucggaaucgcuaguaaucguggaucagaaugccacggugaauacgu
ucccgg
<<<.<<.<<<<<...<<<<<<<<<<......<<........>>.......
...<<<<<<<......<<<<<<<..<<<<<<<....>>>>>>>...<<..
..>>..>>>>>.>>.<<<.<<<..<<<<<<.......<<<<<<<<<....
>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<....<<.
.<<<.....>>>>>.....>>>>>>.....<<<<<.....>>>>>.....
...>>>>.........>>>...>>>>>>>>>...>>>>>>>...>>.>>>
>>>>>.....<<<<<<<.....<<<..<<...<<<....>>>...>>...
.>>>.....>>>>>>>......<....<<<<<<<........>>>>>>>.
...>......>>>>>....<<<<<<<.........>>>>>>>......>>
...>>>
Receptor-Ligand Complex Structure
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PDB7afh A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Resolution3.59 Å
Binding residue
(original residue number in PDB)		G2 Q3 K4 V5 S154 G155 R156 I162 A163 W167 R169 R172 P174 L175 H176 T177 L178 R179 E188 T192 Y193 G194 V195 G197 K199
Binding residue
(residue number reindexed from 1)		G1 Q2 K3 V4 S153 G154 R155 I161 A162 W166 R168 R171 P173 L174 H175 T176 L177 R178 E187 T191 Y192 G193 V194 G196 K198
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7afh, PDBe:7afh, PDBj:7afh
PDBsum7afh
PubMed34088665
UniProtP0A7V3|RS3_ECOLI Small ribosomal subunit protein uS3 (Gene Name=rpsC)

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