Structure of PDB 6zt7 Chain C Binding Site BS01

Receptor Information
>6zt7 Chain C (length=491) Species: 76633 (Thermobacillus xylanilyticus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VASRVVVNADRVKGTINRNIYGHFSEHLGRCIYEGLWVGEDSPIPNTNGI
RNDVLEALKQMKIPVLHWPGGCFADEYHWKDGVGPREKRKRMVNTHVIEN
NHFGTHEFMMLCELLGCEPYISGNVGSGTVQEMSEWVEYITFDGESPMAN
WRRENGREKPWRIKYWGVGNENWGCGGNMRAEYYADLYRQFQTYLRNYGD
NKLHKIACGANTADYHWTEVLMKQAAPFMHGLSLHYYTVPGPWEKKGPAT
GFTTDEWWVTLKKALFMDELVTKHSAIMDVYDPDKRIDLIVDEWGTWYDV
EPGTNPGFLYQQNSIRDALVAGATLHIFHRHCDRVRMANIAQLVNVMQSV
ILTEGERMLLTPTYHVFNMFKVHQDAELLDTWESVERTGPEGELPKVSVS
ASRAADGKIHISLCNLDFETGASVDIELRGLNGGVSATGTTLTSGRIDGH
NTFDEPERVKPAPFRDFKLEGGHLNASLPPMSVTVLELTAG
Ligand information
Ligand IDAHR
InChIInChI=1S/C5H10O5/c6-1-2-3(7)4(8)5(9)10-2/h2-9H,1H2/t2-,3-,4+,5+/m0/s1
InChIKeyHMFHBZSHGGEWLO-QMKXCQHVSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C([C@H]1[C@@H]([C@H]([C@@H](O1)O)O)O)O
OpenEye OEToolkits 1.5.0C(C1C(C(C(O1)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@@H]1O[C@@H](O)[C@H](O)[C@H]1O
ACDLabs 10.04OC1C(OC(O)C1O)CO
FormulaC5 H10 O5
Namealpha-L-arabinofuranose;
alpha-L-arabinose;
L-arabinose;
arabinose
ChEMBL
DrugBankDB03142
ZINCZINC000002569310
PDB chain6zt7 Chain C Residue 516 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6zt7 Probing the determinants of the transglycosylation/hydrolysis partition in a retaining alpha-l-arabinofuranosidase.
Resolution1.85 Å
Binding residue
(original residue number in PDB)		E28 G73 C74 E176 E298
Binding residue
(residue number reindexed from 1)		E26 G71 C72 E171 E293
Annotation score4
Enzymatic activity
Enzyme Commision number 3.2.1.55: non-reducing end alpha-L-arabinofuranosidase.
Gene Ontology
Molecular Function
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0046556 alpha-L-arabinofuranosidase activity
Biological Process
GO:0000272 polysaccharide catabolic process
GO:0046373 L-arabinose metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6zt7, PDBe:6zt7, PDBj:6zt7
PDBsum6zt7
PubMed33524585
UniProtO69262

[Back to BioLiP]