Structure of PDB 6zlz Chain C Binding Site BS01

Receptor Information
>6zlz Chain C (length=360) Species: 493803 (Merkel cell polyomavirus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CIPKPGCCPNVASVPKLLVKGGVEVLSVVTGEDSITQIELYLNPRMGVNS
PDLPTTSNWYTYTYDLQPKGSSPDQPIKENLPAYSVARVSLPMLNEDITC
DTLQMWEAISVKTEVVGISSLINVHYWDMKRVHDYGAGIPVSGVNYHMFA
IGGEPLDLQGLVLDYQTQYPKTTNGGPITIETVLGRKMTPKNQGLDPQAK
AKLDKDGNYPIEVWCPDPSKNENSRYYGSIQTGSQTPTVLQFSNTLTTVL
LDENGVGPLCKGDGLFISCADIVGFLFKTSGKMALHGLPRYFNVTLRKRW
VKNPYPVVNLINSLFSNLMPKVSGQPMEGKDNQVEEVRIYEGSEQLPGDP
DIVRFLDKFG
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6zlz Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6zlz Structure of Merkel Cell Polyomavirus Capsid and Interaction with Its Glycosaminoglycan Attachment Receptor.
Resolution3.52 Å
Binding residue
(original residue number in PDB)		S236 E239
Binding residue
(residue number reindexed from 1)		S219 E222
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
GO:0046872 metal ion binding
Cellular Component
GO:0019028 viral capsid
GO:0042025 host cell nucleus
GO:0044423 virion component

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Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:6zlz, PDBe:6zlz, PDBj:6zlz
PDBsum6zlz
PubMed32699083
UniProtB0G0W3

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